https://genetics.bwh.harvard.edu/wiki/!cassa/ 2026-04-17T06:24:36+00:00 https://genetics.bwh.harvard.edu/wiki/!cassa/ https://genetics.bwh.harvard.edu/wiki/!cassa/_media/wiki:logo.png text/html 2018-04-05T21:44:33+00:00 Anonymous (anonymous@undisclosed.example.com) https://genetics.bwh.harvard.edu/wiki/!cassa/contacts?rev=1522964673&do=diff Contact Information Harvard Medical School New Research Building Brigham and Women’s Hospital, Division of Genetics 77 Avenue Louis Pasteur, Room 464 Boston, MA 02115ccassa _at_ hms.harvard.edu Phone: 617-525-4757 Fax: 617-525-4705 text/html 2024-09-12T19:20:47+00:00 Anonymous (anonymous@undisclosed.example.com) https://genetics.bwh.harvard.edu/wiki/!cassa/opportunities?rev=1726168847&do=diff Opportunities Graduate Students We currently have openings for funded graduate student positions, for individuals who are already admitted to a graduate program at Harvard Medical School within the Harvard Integrated Life Science programs, or Harvard University. Please email CV and statement of interest to ccassa@bwh.harvard.edu. text/html 2026-03-02T23:55:58+00:00 Anonymous (anonymous@undisclosed.example.com) https://genetics.bwh.harvard.edu/wiki/!cassa/publications?rev=1772495758&do=diff Selected Recent Publications Cassa CA<https://doi.org/10.64898/2026.02.28.26347206>Cassa C<https://doi.org/10.1101/2024.12.31.24319792>Cassa CACassa CA<https://doi.org/10.1016/j.xgen.2024.100667><https://doi.org/10.1038/s41588-024-01726-6>Cassa CACassa CA<https://doi.org/10.1101/2023.01.06.23284281>Cassa, CA<https://t.co/mOD0P53Ppn>Cassa CA<https://doi.org/10.1016/j.xgen.2023.100304>Cassa CA*, <https://elifesciences.org/articles/74970><https://doi.org/10.7554/eLife.74970>Cassa CA<https://doi.org… text/html 2016-08-15T20:27:47+00:00 Anonymous (anonymous@undisclosed.example.com) https://genetics.bwh.harvard.edu/wiki/!cassa/research?rev=1471292867&do=diff Research The Cassa Research Group conducts predictive analytic research in two major application areas: the pathogenicity assessment of genomic variants and the clinical application of predictive algorithms in genomics. These applications draw on approaches to enable unprecedented extraction of information from existing data sources. text/html 2023-01-30T22:51:26+00:00 Anonymous (anonymous@undisclosed.example.com) https://genetics.bwh.harvard.edu/wiki/!cassa/resources?rev=1675119086&do=diff Clintegrate: Integrated predictions of clinical risk Clintegrate provides clinical risk assessments that are personalized for individuals who carry genetic variants in well-known disease genes such as BRCA1 and LDLR. Many healthy people carry genetic variants in these disease genes, yet the risk of developing the related disorder is low for most of them. text/html 2023-01-30T21:59:01+00:00 Anonymous (anonymous@undisclosed.example.com) https://genetics.bwh.harvard.edu/wiki/!cassa/start?rev=1675115941&do=diff Home Research Our research group studies the statistical genetics of Mendelian disorders. We focus on two major application areas: methods to assess the pathogenicity of individual genomic variants, and methods to predict the clinical impact of such variants in the context of an individual's existing clinical and genetic risk factors.