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The Sunyaev Lab is a computational genomics laboratory at Department of Biomedical Informatics, Harvard Medical School and Genetics Division of Brigham & Women's Hospital and Harvard Medical School. The primary focus of research in the lab is on genetic variation, including the biology and evolution of mutation, the effect of variation on molecular function and structure, population genetics as a lens on evolution, and the maintenance and allelic architecture of complex traits. We develop computational and statistical methods for sequencing studies. We also have projects in cancer genomics and applied human genetics. The lab encompasses a wide range of skills, backgrounds, and interests spanning these topics.

We are involved in the following graduate programs:

• Biological & Biomedical Sciences Program at the Division of Medical Sciences, Harvard Medical School
• Harvard Biophysics Program
• Harvard Bioinformatics and Integrative Genomics Program
• Program in Quantitative Genomics at the Harvard School of Public Health

Lab involvements:

• Medical and Population Genetics Program at the Broad Institute of MIT and Harvard
• Boston Evolutionary Genomics Supergroup