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start [2021/06/17 00:00]
ivan
start [2021/06/20 18:23] (current)
ivan
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 Explore navigation menu on the left to find out more [[about|About]] PolyPhen-2, consult the [[docs|Documentation]] (work in progress), or [[downloads|Download]] standalone software, datasets and publications. Explore navigation menu on the left to find out more [[about|About]] PolyPhen-2, consult the [[docs|Documentation]] (work in progress), or [[downloads|Download]] standalone software, datasets and publications.
  
-You can also [[http://ikura.partners.org/pph2/|Query]] PolyPhen-2 web server, including bulk submission in [[http://ikura.partners.org/pph2/bgi.shtml|Batch query]] mode.+You can also [[http://genetics.bwh.harvard.edu/pph2/|Query]] PolyPhen-2 web server, including bulk submission in [[http://genetics.bwh.harvard.edu/pph2/bgi.shtml|Batch query]] mode.
  
 Precomputed set of whole human exome sequence space ([[downloads#datasets|WHESS]]) PolyPhen-2 annotations is also available, comprising ~150,000,000 putative single-nucleotide non-synonymous (missense) codon changes enumerated for each CDS codon position in the exons of 43,043 UCSC knownGene human transcripts (hg19/GRCh37). PolyPhen-2 predictions were calculated for all resulting amino acid residue substitutions in human UniProtKB proteins with the maximum CDS sequence overlap and identity. Precomputed set of whole human exome sequence space ([[downloads#datasets|WHESS]]) PolyPhen-2 annotations is also available, comprising ~150,000,000 putative single-nucleotide non-synonymous (missense) codon changes enumerated for each CDS codon position in the exons of 43,043 UCSC knownGene human transcripts (hg19/GRCh37). PolyPhen-2 predictions were calculated for all resulting amino acid residue substitutions in human UniProtKB proteins with the maximum CDS sequence overlap and identity.
  
-Visit PolyPhen-2 [[http://ikura.partners.org/pph2/dbsearch.shtml|WHESS.db]] page to search the database of WHESS annotations.+Visit PolyPhen-2 [[http://genetics.bwh.harvard.edu/pph2/dbsearch.shtml|WHESS.db]] page to search the database of WHESS annotations.
  
start.1623902457.txt.gz ยท Last modified: 2021/06/17 00:00 by ivan