PolyPhen (=Polymorphism Phenotyping) is a tool
which predicts possible impact of an amino acid substitution on the structure
and function of a human protein using straightforward physical and comparative
considerations
- Tue Jul 20 18:46:59 EDT 2010:
- Dear PolyPhen users! Please be aware that this version of the server is no longer maintained nor updated and will
be soon discontinued. You are welcome to switch to PolyPhen-2 instead.
- Sat May 1 21:30:00 EDT 2010:
- Batch query interface to PolyPhen-2 server now accepts genomic SNP coordinates
as input, as well as dbSNP reference SNP numbers (rsIDs). Precomputed dbSNP build 131 PolyPhen-2 annotations for human missense SNPs are
accessible via dbSNP query quick search page and can be downloaded here.
- Wed Mar 31 07:29:00 EDT 2010:
- New version of the PolyPhen web server has been released. PolyPhen-2 includes numerous
improvements, as well as a simple and efficient batch query web interface. Also available
as a standalone software for Linux / Mac OS X.
We would appreciate your feedback.
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