ME728.0
PRECLINICAL COURSES YEAR 1
Molecular Biology of Human Disease
- Credits:
- 4 CREDITS NCE
- Directors:
- R. L. Maas
- Instructors:
- A. H. Sharpe, A. M. Michelson, C. T. Walsh, D. R. Beier, J. M. Cunningham
- Prerequisite:
- Required for 1st year MD/PhD Students.
- Offered:
- July and August.
- Enrollment:
- Max. 20
- Time:
- 9:00 12:00 pm, M.,W.,F.
- Activities/Format:
- Lectures, outside reading.
- Evaluation:
- Term paper, classroom performance.
- Enrollment:
- Max. 20
This 8-week course will provide an in-depth analysis of recent advances in our understanding of human disease pathogenesis, as afforded by contemporary biomedical research in the basic sciences. Topics to be covered include: congenital birth defects, autoimmunity, neurological disease, genetics of hearing, signal transduction, genomic technology, model organisms, cancer genetics, and mechanisms of viral pathogenesis. The course format will consist of individual blocks devoted to the above topics, with lectures, discussions of selected readings, and a final paper. Required for all incoming MD/PhD students. Course Director: Richard Maas, M.D.,Ph.D., and colleagues. Course meetings: July 7-August 15 2003; M, W, F, 9-12am.
BCMP370
Computational Genomic Methods for Predicting Gene Function
- Instructors:
- Frederick Roth and Shamil Sunyaev
- Prerequisites:
- Genetics 224 (Biophysics 101, HT 508) or equivalent, Genetics 201 or equivalent, BCMP 201 or equivalent and some background in probability and statistics.
- Time:
- 1pm - 3pm, F.
- Activities/Format:
- Outside reading, Discussion, Presentations.
- Enrollment:
- Max. 15
This course will focus on computational prediction of gene function from large-scale genomic and proteomic data sets, focusing on recent advances. Each week, three papers will be discussed, preceded by brief introductions by students. Additional historical or review articles will be provided as background material. Session topics will include function prediction based on sequence, structure, expression, comparative genomics, and biological networks. Dates: February 14, March 7, 14, 21, 28, April 4, 11. We will meet in MEC 423 all dates except Mar 14 -- on that date, we will use MEC 334.
Genetics 205
Mammalian Genetics
- Catalog Number
- 9267
- Instructors
- David R. Beier (Medical School)
- Time
- Half course (spring term). W., 10-12.
A literature discussion course on mammalian genetics, including mutation and disease cloning, mutagenesis, comparative genomics, cancer genetics, mammalian development, complex trait genetics in humans and rodents, and mouse genome modification techniques and their applications.
Genetics 316
Transcriptional Regulatory Network Analyses
- Catalog Number
- 2247
- Instructors
- Martha Leonia Bulyk (Medical School) 4259
